SCHEMBL2589431

SCHEMBL2589431

OC1CCCCCCCCCCCCCCCCCN1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
CYP2D6 P10635 2/20 0.38
TSHR P16473 2/20 0.38
LMNA P02545 2/20 0.38
TP53 P04637 2/20 0.38
ALDH1A1 P00352 2/20 0.38
CYP1A2 P05177 1/20 0.38
MLNR O43193 1/20 0.38
ABCB11 O95342 1/20 0.38
EGFR P00533 1/20 0.38
FYN P06241 1/20 0.38
CHRM2 P08172 1/20 0.38
CHRM4 P08173 1/20 0.38
HTR1A P08908 1/20 0.38
CHRM5 P08912 1/20 0.38
ADRA2A P08913 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
CHRM1 P11229 1/20 0.38
ADRA2B P18089 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8845085 1.00 MEN1 (0.38) MEN1KMT2ACYP2D6TSHRLMNA
SCHEMBL12470582 1.00 MEN1 (0.38) MEN1KMT2ACYP2D6TSHRLMNA
SCHEMBL8844911 1.00 MEN1 (0.38) MEN1KMT2ACYP2D6TSHRLMNA
SCHEMBL1059947 1.00
SCHEMBL18534321 1.00 MEN1 (0.38) MEN1KMT2ACYP2D6TSHRLMNA
SCHEMBL19249362 1.00 MEN1 (0.38) MEN1KMT2ACYP2D6TSHRLMNA
Hydrochloric Acid SCHEMBL27758922 0.97
SCHEMBL69143 0.97
Methane SCHEMBL705841 0.94
Hydrochloric Acid SCHEMBL16777054 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997027746-A1 WHITEFLY INSECTICIDE TARGOSZ EUGENE F (US) 1997-08-07 WO claimed
US-12016865-B2 Methods and pharmaceutical compositions for treating candida auris in blood CORMEDIX INC. (US) 2024-06-25 US disclosed
EP-3313857-B1 POLYMER-CYCLODEXTRIN-LIPID CONJUGATES WU NIAN (US) 2021-01-06 EP disclosed
US-10835608-B2 Polymer-carbohydrate conjugates for drug delivery technology LIPOSEUTICALS INC 2020-11-17 US disclosed
EP-3727393-A2 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING CANDIDA AURIS IN BLOOD CorMedix Inc. (US) 2020-10-28 EP disclosed
EP-3077006-B1 POLYMER-CARBOHYDRATE CONJUGATES FOR DRUG DELIVERY TECHNOLOGY WU NIAN (US) 2020-08-19 EP disclosed
US-20190192529-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING CANDIDA AURIS IN BLOOD CORMEDIX INC. 2019-06-27 US disclosed
US-10064954-B2 Polymer-cyclodextrin-lipid conjugates LIPOSEUTICALS INC 2018-09-04 US disclosed
EP-2673000-B1 POLYMER-CARBOHYDRATE-LIPID CONJUGATES WU NIAN (US) 2018-05-16 EP disclosed
EP-3313857-A1 POLYMER-CYCLODEXTRIN-LIPID CONJUGATES Wu, Nian (US) 2018-05-02 EP disclosed
WO-2013003306-A1 PHARMACEUTICAL COMPOSITIONS FOR PARENTERAL ADMINISTRATION WU NIAN (US) 2013-01-03 WO disclosed
US-20130004592-A1 PHARMACEUTICAL COMPOSITIONS FOR PARENTERAL ADMINISTRATION LIPOSEUTICALS, INC. 2013-01-03 US disclosed
US-8304565-B2 PEG-lipid conjugates for liposomes and drug delivery BIOZONE LABORATORIES INC. 2012-11-06 US disclosed
US-20120202890-A1 POLYMER-CARBOHYDRATE-LIPID CONJUGATES WU NIAN (US) 2012-08-09 US disclosed
US-20120202979-A1 POLYMER-CARBOHYDRATE-LIPID CONJUGATES LIPOSEUTICALS, INC. 2012-08-09 US disclosed
WO-2011139343-A2 AMINO ACID LINKED PEG-LIPID CONJUGATES WU NIAN (US) 2011-11-10 WO disclosed
US-20100076209-A1 PEG-lipid conjugates for liposomes and drug delivery BIOZONE LABORATORIES INC. 2010-03-25 US disclosed
US-5658954-A NONTOXIC TO HUMAN, ANIMALS; MIXTURE OF COTTONSEED OIL AMIDE, COCONUT OIL AMIDE, TALL OIL AMIDE, NONIONIC SURFACTANT, CHELATE COMPOUND AND FLOW CONTROL AGENT TARGOSZ EUGENE F (US) 1997-08-19 US disclosed
WO-1997027746-A1 WHITEFLY INSECTICIDE TARGOSZ EUGENE F (US) 1997-08-07 WO disclosed
US-5496857-A ALKANOL AMIDES OF COTTONSEED, COCONUT AND TALL OIL, NONIONIC SURFACTANTS TARGOSZ EUGENE F (US) 1996-03-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100076209-A1 PEG-lipid conjugates for liposomes and drug delivery DAGLA, DAGLB, DGKG MEN1 2105/4885KMT2A 4305/4885CYP2D6 1508/4885
US-10835608-B2 Polymer-carbohydrate conjugates for drug delivery technology LIPC, FABP4, CETP MEN1 2733/4885KMT2A 1977/4885CYP2D6 86/4885
US-20130004592-A1 PHARMACEUTICAL COMPOSITIONS FOR PARENTERAL ADMINISTRATION LIPC, CETP, UGCG MEN1 2846/4885KMT2A 3533/4885CYP2D6 120/4885
US-10064954-B2 Polymer-cyclodextrin-lipid conjugates CETP, FABP4, PLIN3 MEN1 3960/4885KMT2A 4200/4885CYP2D6 79/4885
US-20120202890-A1 POLYMER-CARBOHYDRATE-LIPID CONJUGATES LIPC, FUT6, UGCG MEN1 1849/4885KMT2A 1692/4885CYP2D6 408/4885
US-20120202979-A1 POLYMER-CARBOHYDRATE-LIPID CONJUGATES LIPC, FUT6, UGCG MEN1 1849/4885KMT2A 1692/4885CYP2D6 408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.