Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | ESRRB | O95718 | 1/20 | 0.34 |
| ▸ | ESRRA | P11474 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31312752 | 1.00 | BACE1 (0.37) | BACE1ALDH1A1LMNAPOLBMAPT | |
| SCHEMBL15298621 | 0.81 | BACE1 (0.43) | BACE1ALDH1A1LMNAPOLBMAPT | |
| SCHEMBL6935704 | 0.80 | ALDH1A1 (0.41) | ALDH1A1LMNAPOLBMAPTALOX12 | |
| SCHEMBL13257964 | 0.80 | P2RX3 (0.39) | ALDH1A1LMNAPOLBMAPTALOX12 | |
| SCHEMBL1272528 | 0.79 | ALDH1A1 (0.39) | ALDH1A1LMNAPOLBMAPTALOX12 | |
| SCHEMBL340634 | 0.79 | MDM2 (0.40) | ALDH1A1LMNAPOLBMAPTALOX12 | |
| SCHEMBL339513 | 0.79 | ALDH1A1 (0.43) | ALDH1A1LMNAPOLBMAPTALOX12 | |
| SCHEMBL314775 | 0.79 | ALDH1A1 (0.52) | ALDH1A1LMNAPOLBMAPTALOX12 | |
| SCHEMBL12369333 | 0.79 | MAPT (0.34) | ALDH1A1LMNAPOLBMAPTALOX12 | |
| SCHEMBL3709198 | 0.79 | MAPT (0.34) | ALDH1A1LMNAPOLBMAPTALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148287-B2 | Catalyst immobilization on siliceous mesocellular foam via click chemistry | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2012-04-03 | — | — | US | disclosed |
| US-8148287-B2 | Catalyst immobilization on siliceous mesocellular foam via click chemistry | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2012-04-03 | — | — | US | disclosed |
| US-8067440-B2 | Phosphonium salts derivatives and uses thereof | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2011-11-29 | — | — | US | disclosed |
| US-20110092683-A1 | PHOSPHONIUM SALTS DERIVATIVES AND USES THEREOF | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2011-04-21 | — | — | US | disclosed |
| US-7880037-B2 | Phosphonium supported triphenylphosphine; for controlling solubility of a molecule; oxidation of Cinnamyl Alcohol using above catalyst system | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2011-02-01 | — | — | US | disclosed |
| US-20100105544-A1 | CATALYST IMMOBILIZATION ON SILICEOUS MESOCELLULAR FOAM VIA CLICK CHEMISTRY | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-04-29 | — | — | US | disclosed |
| US-20100105544-A1 | CATALYST IMMOBILIZATION ON SILICEOUS MESOCELLULAR FOAM VIA CLICK CHEMISTRY | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-04-29 | — | — | US | disclosed |
| WO-2008115154-A1 | CATALYST IMMOBILIZATION ON SILICEOUS MESOCELLULAR FOAM VIA CLICK CHEMISTRY | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2008-09-25 | — | — | WO | disclosed |
| EP-1756128-A4 | PHOSPHONIUM SALTS DERIVATIVES AND THEIR USE AS SOLUBILITY CONTROLLING AUXILIARIES | VALORISATION RECH SOC EN COMMA (CA) | 2008-06-25 | — | — | EP | disclosed |
| US-20070197477-A1 | PHOSPHONIUM SALTS DERIVATIVES | VALORISATION-RECHERECHE (CA) | 2007-08-23 | — | — | US | disclosed |
| CN-101018795-A | Phosphonium salts derivatives and their use as solubility controlling auxiliaries | VALORISATION RECH SOC EN COMMA (CA) | 2007-08-15 | — | — | CN | disclosed |
| EP-1756128-A1 | PHOSPHONIUM SALTS DERIVATIVES AND THEIR USE AS SOLUBILITY CONTROLLING AUXILIARIES | Valorisation-Recherche, Société en Commandite (CA) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005097812-A1 | PHOSPHONIUM SALTS DERIVATIVES AND THEIR USE AS SOLUBILITY CONTROLLING AUXILIARIES | Valorisation-Recherche, Société en Commandite (CA) | 2005-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197477-A1 | PHOSPHONIUM SALTS DERIVATIVES | PI4K2A, PIP4K2A, PI4K2B | BACE1 3395/4885ALDH1A1 3806/4885LMNA 783/4885 |
| US-20110092683-A1 | PHOSPHONIUM SALTS DERIVATIVES AND USES THEREOF | PI4K2A, PIP4K2A, PI4K2B | BACE1 3219/4885ALDH1A1 3468/4885LMNA 964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.