Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | JUN | P05412 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16309558 | 0.89 | JUN (0.45) | ALDH1A1KMT2AJUNNFKB1ERN1 | |
| SCHEMBL16957470 | 0.85 | MEN1 (0.40) | KMT2AKDM4EHTTP2RX3 | |
| SCHEMBL16961007 | 0.84 | TACR1 (0.38) | NFKB1LMNASMN1; SMN2 | |
| SCHEMBL339513 | 0.84 | ALDH1A1 (0.43) | ALDH1A1KMT2APOLBIRAK4LMNA | |
| SCHEMBL3673788 | 0.83 | ALDH1A1 (0.36) | ALDH1A1KMT2AMDM2PARP10JUN | |
| SCHEMBL6930848 | 0.81 | ALDH1A3 (0.53) | ALDH1A1ALDH1A3KMT2AMDM2PARP10 | |
| SCHEMBL12885255 | 0.81 | ALDH1A1 (0.41) | ALDH1A1ALDH1A3KMT2APARP10BRD4 | |
| SCHEMBL13257964 | 0.81 | P2RX3 (0.39) | ALDH1A1POLBLMNAMAPTALOX12 | |
| SCHEMBL16309634 | 0.81 | BRD4 (0.38) | ALDH1A1ALDH1A3KMT2AMDM2PARP10 | |
| SCHEMBL6578342 | 0.80 | ALDH1A1 (0.39) | ALDH1A1ALDH1A3KMT2AMDM2PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1058548-B1 | THE USE OF ISATIN AND OXINDOLE DERIVATIVES IN THE PREPARATION OF A MEDICAMENT FOR USE IN THE TREATMENT OF MYCOBACTERIAL DISEASE | ASTRAZENECA AB (SE) | 2003-09-17 | — | — | EP | claimed |
| EP-1371657-A1 | Transition-metal complexes and use thereof in transition-metal catalysed reactions.. | Bayer Aktiengesellschaft (DE) | 2003-12-17 | — | — | EP | disclosed |
| US-20030220512-A1 | Novel transition metal complexes and their use in transition metal-catalysed reactions | BAYER AKTIENGESELLSCHAFT (DE) | 2003-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220512-A1 | Novel transition metal complexes and their use in transition metal-catalysed reactions | AP1M1, AP3M1, CYC1 | ALDH1A1 1042/4885ALDH1A3 3225/4885KMT2A 3801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.