Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2595461 | 0.83 | HTT (0.63) | CYP1A2HTTALDH1A1MEN1KMT2A | |
| SCHEMBL6993091 | 0.72 | HTT (0.73) | HTTALDH1A1KMT2AGAALMNA | |
| SCHEMBL12189396 | 0.72 | KMT2A (0.69) | CYP1A2HTTALDH1A1MEN1KMT2A | |
| SCHEMBL7417220 | 0.71 | HTT (0.71) | HTTALDH1A1KMT2AGAALMNA | |
| SCHEMBL477006 | 0.71 | ALDH1A1 (0.59) | CYP1A2HTTALDH1A1MEN1KMT2A | |
| SCHEMBL12173079 | 0.71 | PARP1 (0.56) | CYP1A2HTTALDH1A1MEN1KMT2A | |
| SCHEMBL29790438 | 0.71 | ACE2 (0.70) | CYP1A2ALDH1A1MEN1KMT2APTPN1 | |
| SCHEMBL15490693 | 0.71 | ACE2 (0.70) | CYP1A2ALDH1A1MEN1KMT2APTPN1 | |
| Water SCHEMBL7417216 | 0.71 | HTT (0.70) | HTTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL6754115 | 0.70 | DHODH (0.60) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011138665-A1 | NOVEL IMMUNOMODULATOR AND ANTI INFLAMMATORY COMPOUNDS | INCOZEN THERAPEUTICS PVT. LTD. (IN) | 2011-11-10 | — | — | WO | disclosed |