Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.55 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12189396 | 0.86 | KMT2A (0.69) | HTTKMT2ACYP1A2KDM4EKCNK3 | |
| SCHEMBL6993091 | 0.86 | HTT (0.73) | HTTKMT2AGAAPOLBKDM4E | |
| SCHEMBL7417220 | 0.85 | HTT (0.71) | HTTKMT2AGAAPOLBKDM4E | |
| SCHEMBL12172778 | 0.84 | CYP1A2 (0.72) | HTTKMT2ACYP1A2GAAPOLB | |
| Water SCHEMBL7417216 | 0.84 | HTT (0.70) | HTTKMT2AGAAPOLBKDM4E | |
| SCHEMBL2589595 | 0.83 | CYP1A2 (0.50) | HTTKMT2ACYP1A2GAAPOLB | |
| SCHEMBL29788303 | 0.82 | CYP11B1 (0.56) | HTTKMT2APOLBKDM4EMEN1 | |
| SCHEMBL2492334 | 0.82 | CTSV (0.65) | HTTKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL11459070 | 0.81 | HTT (0.73) | HTTKMT2ACYP1A2KDM4EKCNK3 | |
| SCHEMBL6993922 | 0.81 | HTT (0.73) | HTTKMT2AGAAPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011138665-A1 | NOVEL IMMUNOMODULATOR AND ANTI INFLAMMATORY COMPOUNDS | INCOZEN THERAPEUTICS PVT. LTD. (IN) | 2011-11-10 | — | — | WO | disclosed |