SCHEMBL2589686

SCHEMBL2589686

CCCCc1cccc(-n2nc3ccc(Cl)cc3n2)c1O

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 8/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
ALOX5 P09917 1/20 0.37
PTGS2 P35354 1/20 0.37
MAPK8 P45983 1/20 0.34
IAPP P10997 1/20 0.33
TP53 P04637 1/20 0.33
MAPT P10636 1/20 0.33
CNR2 P34972 1/20 0.33
ELANE P08246 1/20 0.33
CTSG P08311 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9869340 0.87 GABRA1 (0.42) NPC1RAB9AMEN1KMT2ATP53
SCHEMBL27503559 0.86 ALOX5 (0.43) ADORA3NPC1RAB9AALOX5PTGS2
SCHEMBL1532693 0.84 NPC1 (0.49) ADORA3NPC1RAB9AMEN1KMT2A
SCHEMBL29756256 0.84 ADORA3 (0.39) ADORA3NPC1RAB9AMEN1KMT2A
SCHEMBL4949050 0.84 ADORA3 (0.39) ADORA3NPC1RAB9AMEN1KMT2A
SCHEMBL27466289 0.82 ADORA3 (0.36) ADORA3NPC1RAB9AALOX5PTGS2
SCHEMBL7874799 0.81 NPC1 (0.39) NPC1RAB9AMEN1KMT2ATP53
SCHEMBL9436836 0.81 NPC1 (0.36) ADORA3NPC1RAB9AMEN1KMT2A
SCHEMBL27464195 0.81 NPC1 (0.36) ADORA3NPC1RAB9AMEN1KMT2A
SCHEMBL10428944 0.81 ADORA3 (0.35) ADORA3MEN1KMT2AMAPK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1902180-A Use of 4-cyano-naphthalene-1, 8-dicarboximide derivatives and related compounds for protecting organic materials from the damaging effects of light BASF AG (DE) 2007-01-24 CN claimed
EP-3320135-B1 ELECTRET WEBS WITH CHARGE-ENHANCING ADDITIVES 3M INNOVATIVE PROPERTIES CO (US) 2019-08-28 EP disclosed
CN-103732600-A Plasticizers and optical films MERCK PATENT GMBH 2014-04-16 CN disclosed
CN-102341456-B Aromatic polycarbonate resin composition, process for producing resin composition, and molded article MITSUBISHI ENGINERRING PLASTICS CORP 2014-01-08 CN disclosed
CN-102844377-A Transparent, fire-retardant aromatic polycarbonate resin composition and molded product MITSUBISHI GAS CHEMICAL CO 2012-12-26 CN disclosed
CN-102341456-A Aromatic polycarbonate resin composition, process for producing resin composition, and molded article MITSUBISHI ENG PLASTICS CORP 2012-02-01 CN disclosed
CN-101495557-B Improved processing conditions of polyethylene articles during their preparation by melt processing CLARIANT FINANCE BVI LTD 2012-01-11 CN disclosed
CN-102257063-A Stabilized dynamically vulcanized thermoplastic elastomer compositions useful in fluid barrier applications EXXONMOBIL CHEM PATENTS INC 2011-11-23 CN disclosed
WO-2011137321-A1 THICKENED COMPOSITONS OF HIGH PH ISP INVESTMENTS INC. (US) 2011-11-03 WO disclosed
CN-1902180-B Use of 4-cyano-naphthalene-1, 8-dicarboximide derivatives and related compounds for protecting organic materials from the damaging effects of light BASF AG 2010-08-25 CN disclosed
CN-101495557-A Improved processing conditions of polyethylene articles during their preparation by melt processing CLARIANT FINANCE BVI LTD (VG) 2009-07-29 CN disclosed
CN-1980975-A Sulfonated aromatic copolyesters containing hydroxyalkanoic acid groups and shaped articles produced therefrom DU PONT (US) 2007-06-13 CN disclosed
CN-1980976-A Copolyetherester compositions containing hydroxyalkanoic acids and shaped articles produced therefrom DU PONT (US) 2007-06-13 CN disclosed
CN-1902180-A Use of 4-cyano-naphthalene-1, 8-dicarboximide derivatives and related compounds for protecting organic materials from the damaging effects of light BASF AG (DE) 2007-01-24 CN disclosed
EP-1194515-A1 HARD SURFACE CLEANING COMPOSITION COMPRISING A UVA-FILTER UNILEVER N.V. (NL) 2002-04-10 EP disclosed
WO-2001004251-A1 HARD SURFACE CLEANING COMPOSITION COMPRISING A UVA-FILTER UNILEVER N.V. (NL) 2001-01-18 WO disclosed