Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7874799 | 0.88 | NPC1 (0.39) | NPC1RAB9AMAPTKDM4EATM | |
| SCHEMBL2589686 | 0.87 | ADORA3 (0.39) | NPC1RAB9AMAPTTP53MEN1 | |
| SCHEMBL13121650 | 0.84 | GABRA1 (0.52) | GABRA1GABRB2NPC1RAB9AKDM4E | |
| SCHEMBL31155592 | 0.83 | NPC1 (0.51) | NPC1RAB9AMAPTKDM4EATM | |
| SCHEMBL5697093 | 0.83 | NPC1 (0.53) | NPC1RAB9AMAPTKDM4EATM | |
| SCHEMBL29492042 | 0.83 | NPC1 (0.41) | NPC1RAB9AMAPTKDM4EATM | |
| SCHEMBL17940508 | 0.83 | NPC1 (0.41) | NPC1RAB9AMAPTKDM4EATM | |
| SCHEMBL19119905 | 0.82 | NPC1 (0.39) | NPC1RAB9AMAPTKDM4EATM | |
| SCHEMBL10873172 | 0.82 | NPC1 (0.48) | NPC1RAB9AMAPTKDM4EATM | |
| SCHEMBL30426108 | 0.81 | CA2 (0.42) | GABRA1GABRB2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019614-A | Stabilized polymers | SHELL OIL COMPANY (US) | 1991-05-28 | — | — | US | disclosed |