Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 10/20 | 0.43 |
| ▸ | TIPARP | Q7Z3E1 | 6/20 | 0.37 |
| ▸ | TNF | P01375 | 3/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25898373 | 0.83 | NPC1 (0.40) | GRM2TIPARPTNFHDAC3HDAC1 | |
| SCHEMBL25898159 | 0.82 | TIPARP (0.43) | GRM2TIPARPTNFHDAC3HDAC1 | |
| SCHEMBL25899760 | 0.81 | TIPARP (0.41) | GRM2TIPARPTNFHDAC3HDAC1 | |
| SCHEMBL25898407 | 0.80 | TIPARP (0.48) | GRM2TIPARPTNFHDAC3HDAC1 | |
| SCHEMBL25897799 | 0.80 | TIPARP (0.41) | GRM2TIPARPTNFHDAC3HDAC1 | |
| SCHEMBL25898617 | 0.79 | TIPARP (0.41) | GRM2TIPARPTNF | |
| SCHEMBL25898347 | 0.79 | BRD4 (0.40) | GRM2TIPARPTNFHDAC3HDAC1 | |
| SCHEMBL25898391 | 0.79 | TIPARP (0.46) | GRM2TIPARPTNFHDAC3HDAC1 | |
| SCHEMBL26789113 | 0.79 | TIPARP (0.48) | GRM2TIPARPTNFHDAC3HDAC1 | |
| SCHEMBL25898742 | 0.77 | TIPARP (0.46) | GRM2TIPARPTNFHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |