Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 6/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.39 |
| ▸ | TNF | P01375 | 5/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25898605 | 0.89 | TIPARP (0.49) | TIPARPGRM2TNF | |
| SCHEMBL25898407 | 0.88 | TIPARP (0.48) | TIPARPGRM2TNF | |
| SCHEMBL25898373 | 0.85 | NPC1 (0.40) | TIPARPGRM2TNF | |
| SCHEMBL25898823 | 0.85 | GRM2 (0.37) | GRM2PTGESPDE10AMAT2A | |
| SCHEMBL25897799 | 0.82 | TIPARP (0.41) | TIPARPGRM2TNFPTGES | |
| SCHEMBL25899760 | 0.80 | TIPARP (0.41) | TIPARPGRM2TNF | |
| SCHEMBL25898347 | 0.79 | BRD4 (0.40) | TIPARPGRM2TNF | |
| SCHEMBL25898123 | 0.79 | GRM2 (0.43) | TIPARPGRM2TNF | |
| SCHEMBL26786720 | 0.79 | TIPARP (0.44) | TIPARPGRM2TNF | |
| SCHEMBL25322527 | 0.79 | TIPARP (0.67) | TIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |