Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TNF | P01375 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | TIPARP | Q7Z3E1 | 2/20 | 0.37 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25898373 | 0.85 | NPC1 (0.40) | GRM2TLR8SMN1; SMN2NPC1RAB9A | |
| SCHEMBL25898407 | 0.82 | TIPARP (0.48) | GRM2NPC1RAB9ATNFTIPARP | |
| SCHEMBL25897799 | 0.82 | TIPARP (0.41) | GRM2TLR8SMN1; SMN2KDM4ETNF | |
| SCHEMBL25899760 | 0.81 | TIPARP (0.41) | GRM2TLR8SMN1; SMN2NPC1RAB9A | |
| SCHEMBL25898391 | 0.81 | TIPARP (0.46) | GRM2SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL25898617 | 0.79 | TIPARP (0.41) | GRM2TNFTIPARP | |
| SCHEMBL25898123 | 0.79 | GRM2 (0.43) | GRM2TNFTIPARPHDAC3HDAC1 | |
| SCHEMBL25898742 | 0.77 | TIPARP (0.46) | GRM2TLR8SMN1; SMN2KDM4ETNF | |
| SCHEMBL25897832 | 0.77 | TIPARP (0.49) | GRM2TLR8SMN1; SMN2NPC1RAB9A | |
| SCHEMBL25899897 | 0.77 | TIPARP (0.51) | GRM2TLR8SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |