SCHEMBL25898411

SCHEMBL25898411

COCc1cc(CCC(C)(c2cc(COC)c(O)c(COC)c2)c2cc(COC)c(O)c(COC)c2)cc(COC)c1O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCE Q02156 3/20 0.39
MYLK Q15746 2/20 0.39
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
PRKCG P05129 1/20 0.39
MAPT P10636 1/20 0.39
PRKCA P17252 1/20 0.39
APEX1 P27695 1/20 0.39
RECQL P46063 1/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CYP2C19 P33261 1/20 0.34
ALOX15 P16050 1/20 0.34
MAPK1 P28482 1/20 0.34
HTT P42858 1/20 0.34
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.33
HIF1A Q16665 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CALM1 P0DP23 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25898413 0.95 PRKCE (0.36) PRKCEMYLKMEN1ALDH1A1PRKCG
SCHEMBL25898412 0.92 SHBG (0.39) PRKCEMYLKMEN1ALDH1A1PRKCG
SCHEMBL26095915 0.88 PRKCE (0.44) PRKCEMYLKMEN1ALDH1A1PRKCG
SCHEMBL10455314 0.85 PRKCE (0.40) PRKCEMYLKMEN1ALDH1A1PRKCG
SCHEMBL25898418 0.85 CYP2D6 (0.34) CYP2C19CYP2C9TSHRHSD17B10
SCHEMBL25898419 0.82 CYP2D6 (0.34) CYP2C19CYP2C9TSHRHSD17B10
SCHEMBL25898408 0.81 SHBG (0.42) ALDH1A1CYP2C19ALOX15MAPK1HTT
SCHEMBL10452200 0.80 ESR1 (0.40) PRKCEMYLKMEN1ALDH1A1PRKCG
SCHEMBL25898410 0.79 SHBG (0.53) ALDH1A1CYP2C19ALOX15MAPK1HTT
SCHEMBL15959536 0.79 PRKCE (0.35) PRKCEMYLKMEN1ALDH1A1PRKCG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230234905-A1 NOVEL TRISPHENOL DERIVATIVE HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2023-07-27 US disclosed
US-20230234905-A1 NOVEL TRISPHENOL DERIVATIVE HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2023-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230234905-A1 NOVEL TRISPHENOL DERIVATIVE TTPA, CDK2AP2, CDKL2 PRKCE 3846/4885MYLK 3297/4885MEN1 4624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.