SCHEMBL25898408

SCHEMBL25898408

CC(CCc1cc(CO)c(O)c(CO)c1)(c1cc(CO)c(O)c(CO)c1)c1cc(CO)c(O)c(CO)c1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.42
KLF10 Q13118 1/20 0.41
KDM4E B2RXH2 2/20 0.39
CASP6 P55212 1/20 0.39
CYP2C19 P33261 1/20 0.37
ALOX15 P16050 1/20 0.37
MAPK1 P28482 1/20 0.37
HTT P42858 1/20 0.37
HSD17B10 Q99714 2/20 0.36
CYP2C9 P11712 1/20 0.36
TSHR P16473 1/20 0.36
HIF1A Q16665 1/20 0.36
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
HSPA5 P11021 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25898410 0.94 SHBG (0.53) SHBGKLF10KDM4ECASP6CYP2C19
SCHEMBL25898409 0.90 SHBG (0.57) SHBGKLF10KDM4ECASP6CYP2C19
SCHEMBL25898416 0.84 NUDT1 (0.34) SHBGKLF10KDM4ECYP2C19HSD17B10
SCHEMBL25898411 0.81 PRKCE (0.39) CYP2C19ALOX15MAPK1HTTHSD17B10
SCHEMBL25898426 0.81 CYP2C19 (0.62) KDM4ECYP2C19ALOX15MAPK1HTT
SCHEMBL25898417 0.81 NUDT1 (0.36) SHBGKLF10KDM4ECYP2C19HSD17B10
SCHEMBL25898413 0.78 PRKCE (0.36) SHBGCYP2C19ALOX15MAPK1HTT
SCHEMBL25898430 0.77 CYP2C19 (0.55) SHBGKDM4ECYP2C19ALOX15MAPK1
SCHEMBL3686389 0.76 PTGS1 (0.47) SHBGKDM4ECYP2C19HSD17B10CYP2C9
SCHEMBL25898412 0.74 SHBG (0.39) SHBGCYP2C19HSD17B10CYP2C9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230234905-A1 NOVEL TRISPHENOL DERIVATIVE HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2023-07-27 US disclosed
US-20230234905-A1 NOVEL TRISPHENOL DERIVATIVE HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2023-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230234905-A1 NOVEL TRISPHENOL DERIVATIVE TTPA, CDK2AP2, CDKL2 SHBG 131/4885KLF10 2714/4885KDM4E 1902/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.