Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15769506 | 0.88 | GPR119 (0.43) | GPR119KDM4EMAPTTHRB | |
| SCHEMBL25898943 | 0.87 | GPR119 (0.53) | GPR119MEN1KMT2AKDM4EMAPT | |
| SCHEMBL25898980 | 0.87 | MEN1 (0.48) | GPR119MEN1KMT2AKDM4EMAPT | |
| SCHEMBL25899063 | 0.86 | GPR119 (0.45) | GPR119MEN1KMT2AKDM4EMAPT | |
| SCHEMBL16818208 | 0.86 | GPR119 (0.52) | HPGDSGPR119TP53MEN1KMT2A | |
| SCHEMBL25899022 | 0.84 | GPR119 (0.42) | HPGDSGPR119TP53GRM5GRM1 | |
| SCHEMBL15769716 | 0.81 | GPR119 (0.47) | GPR119KDM4EMAPTTHRB | |
| SCHEMBL25571982 | 0.78 | GPR119 (0.49) | HPGDSGPR119TP53MEN1KMT2A | |
| SCHEMBL15781325 | 0.78 | DDB1 (0.41) | GPR119 | |
| SCHEMBL15781336 | 0.78 | GPR119 (0.42) | GPR119KDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114858-A1 | BENZOFURAN AND BENZOTHIOPHENE PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |