Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 2/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | CTSE | P14091 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25899063 | 0.89 | GPR119 (0.45) | MEN1KMT2AALDH1A1GPR119KDM4E | |
| SCHEMBL25899021 | 0.87 | HPGDS (0.47) | MEN1KMT2AGPR119MKNK1KDM4E | |
| SCHEMBL15769506 | 0.87 | GPR119 (0.43) | DDB1CRBNSTSGPR119KDM4E | |
| SCHEMBL25898943 | 0.86 | GPR119 (0.53) | MEN1KMT2ASTSGPR119KDM4E | |
| SCHEMBL22324973 | 0.86 | MEN1 (0.54) | MEN1KMT2AALDH1A1STSTGFBR1 | |
| SCHEMBL25898964 | 0.85 | DDB1 (0.44) | MEN1KMT2ADDB1CRBNALDH1A1 | |
| SCHEMBL15769716 | 0.80 | GPR119 (0.47) | ALDH1A1GPR119HTTKDM4EMAPT | |
| SCHEMBL15781336 | 0.77 | GPR119 (0.42) | DDB1CRBNSTSGPR119KDM4E | |
| SCHEMBL15781325 | 0.77 | DDB1 (0.41) | DDB1CRBNGPR119BACE1 | |
| SCHEMBL25899064 | 0.75 | LIPE (0.42) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114858-A1 | BENZOFURAN AND BENZOTHIOPHENE PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |