Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.45 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25898980 | 0.89 | MEN1 (0.48) | GPR119KDM4EMAPTTHRBMEN1 | |
| SCHEMBL1810911 | 0.87 | GPR119 (0.50) | GPR119LIPEMGLLKCNH2SCN5A | |
| SCHEMBL25899021 | 0.86 | HPGDS (0.47) | GPR119KDM4EMAPTTHRBMEN1 | |
| SCHEMBL25899064 | 0.86 | LIPE (0.42) | GPR119LIPEMGLLKCNH2SCN5A | |
| SCHEMBL15769506 | 0.84 | GPR119 (0.43) | GPR119KDM4EMAPTTHRB | |
| SCHEMBL25898943 | 0.83 | GPR119 (0.53) | GPR119KDM4EMAPTTHRBMEN1 | |
| SCHEMBL15769716 | 0.77 | GPR119 (0.47) | GPR119KDM4EMAPTTHRBALDH1A1 | |
| SCHEMBL25864470 | 0.76 | GPR119 (0.52) | GPR119LIPEMGLLHSD11B1KDM4E | |
| SCHEMBL30898354 | 0.76 | ABHD6 (0.53) | GPR119LIPEMGLLPIM1NOTUM | |
| SCHEMBL30409654 | 0.76 | ABHD6 (0.53) | GPR119LIPEMGLLPIM1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114858-A1 | BENZOFURAN AND BENZOTHIOPHENE PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |