SCHEMBL25899022

SCHEMBL25899022

CC(C)(C)OC(=O)N1CCCC(=O)C(Sc2cccc(F)c2)C1

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 2/20 0.42
USP30 Q70CQ3 4/20 0.40
GRM5 P41594 1/20 0.40
GRM1 Q13255 1/20 0.40
HPGDS O60760 2/20 0.39
MKNK1 Q9BUB5 1/20 0.38
BRD3 Q15059 1/20 0.38
TGM2 P21980 1/20 0.38
TP53 P04637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15781327 0.88 USP30 (0.40) GPR119USP30
SCHEMBL25898944 0.87 USP30 (0.44) GPR119USP30HPGDS
SCHEMBL25898964 0.87 DDB1 (0.44) USP30MKNK1
SCHEMBL25899064 0.86 LIPE (0.42) GPR119USP30
SCHEMBL25899021 0.84 HPGDS (0.47) GPR119GRM5GRM1HPGDSMKNK1
SCHEMBL15781325 0.81 DDB1 (0.41) GPR119USP30
SCHEMBL15769035 0.81 FPR2 (0.45) GPR119USP30MKNK1
SCHEMBL16818208 0.78 GPR119 (0.52) GPR119HPGDSTP53
SCHEMBL15781353 0.74 RORC (0.44) GPR119USP30MKNK1
SCHEMBL15769506 0.72 GPR119 (0.43) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023114858-A1 BENZOFURAN AND BENZOTHIOPHENE PSYCHOPLASTOGENS AND USES THEREOF DELIX THERAPEUTICS, INC. (US) 2023-06-22 WO disclosed