SCHEMBL25899207

SCHEMBL25899207

CC(C)c1ccc(CCCCc2cc3c(=O)nc(N)[nH]c3[nH]2)cn1

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GART P22102 16/20 0.45
FOLR1 P15328 11/20 0.45
SLC46A1 Q96NT5 10/20 0.45
FOLR2 P14207 9/20 0.45
SLC19A1 P41440 5/20 0.45
XDH P47989 1/20 0.34
PARP1 P09874 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25904120 0.86 GART (0.44) GARTFOLR1SLC46A1FOLR2SLC19A1
SCHEMBL25899174 0.67 DHFR (0.38) XDH
SCHEMBL23583491 0.66 ESR1 (0.40)
SCHEMBL24451674 0.66 RAB9A (0.49)
SCHEMBL22725670 0.65 RAB9A (0.51)
SCHEMBL8259759 0.65 NFKB1 (0.51)
SCHEMBL21921107 0.63 ESR1 (0.37)
SCHEMBL18552695 0.62 GART (0.69) GARTFOLR1SLC46A1FOLR2SLC19A1
SCHEMBL24629146 0.62 CYP3A4 (0.42) XDHPARP1
SCHEMBL22526065 0.62 NFKB1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230279426-A1 MODIFIED VIRAL COMPOSITIONS FOR VIRAL TRANSDUCTION LYCIA THERAPEUTICS, INC. 2023-09-07 US disclosed
US-20230226214-A1 BIFUNCTIONAL BRIDGING COMPOSITIONS FOR VIRAL TRANSDUCTION LYCIA THERAPEUTICS, INC. 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226214-A1 BIFUNCTIONAL BRIDGING COMPOSITIONS FOR VIRAL TRANSDUCTION HAVCR2, FCGR3B, FCGR2A GART 1094/4885FOLR1 297/4885SLC46A1 1864/4885
US-20230279426-A1 MODIFIED VIRAL COMPOSITIONS FOR VIRAL TRANSDUCTION HAVCR2, ASGR1, FCGR3B GART 1597/4885FOLR1 451/4885SLC46A1 2039/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.