Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.39 |
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | NFATC1 | O95644 | 2/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | HASPIN | Q8TF76 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | PRKCB | P05771 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCH | P24723 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29856149 | 0.76 | ERN1 (0.39) | ADORA3ADORA2ADYRK1AGSK3BNFATC1 | |
| SCHEMBL1609661 | 0.73 | ADORA3 (0.54) | ADORA3ADORA2ADYRK1AGSK3BNFATC1 | |
| SCHEMBL25617163 | 0.71 | TOP2A (0.37) | ADORA3ADORA2ADYRK1AGSK3BNFATC1 | |
| SCHEMBL29856230 | 0.70 | ROCK2 (0.42) | ADORA3ADORA2AROCK2LMNAMAPT | |
| SCHEMBL23229478 | 0.68 | DYRK1A (0.36) | DYRK1AGSK3BNFATC1KCNH2HASPIN | |
| SCHEMBL2628358 | 0.67 | ADORA3 (0.49) | ADORA3ADORA2ADYRK1AGSK3BNFATC1 | |
| SCHEMBL9968083 | 0.67 | ADORA3 (0.40) | ADORA3ADORA2ADYRK1AGSK3BNFATC1 | |
| SCHEMBL23380303 | 0.67 | DYRK1A (0.42) | ADORA3ADORA2ADYRK1AGSK3BNFATC1 | |
| SCHEMBL14191776 | 0.66 | ADORA3 (0.51) | ADORA3ADORA2ADYRK1AGSK3BNFATC1 | |
| SCHEMBL30929605 | 0.66 | GPR3 (0.64) | ADORA3ADORA2ADYRK1AGSK3BNFATC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11702409-B2 | Pyrazolyl derivatives useful as anti-cancer agents | NOVARTIS AG (CH) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702409-B2 | Pyrazolyl derivatives useful as anti-cancer agents | PAK5, CYP51A1, SF3B5 | ADORA3 1182/4885ADORA2A 2161/4885DYRK1A 2563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.