Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.46 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.43 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.43 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.43 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.43 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.43 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.43 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.43 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.43 |
| ▸ | CACNG1 | Q06432 | 2/20 | 0.43 |
| ▸ | CACNB2 | Q08289 | 2/20 | 0.43 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.43 |
| ▸ | CACNA1E | Q15878 | 2/20 | 0.43 |
| ▸ | CACNA2D4 | Q7Z3S7 | 2/20 | 0.43 |
| ▸ | CACNA2D3 | Q8IZS8 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25900061 | 0.90 | CACNB4 (0.42) | GPR119CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL25263211 | 0.90 | GPR119 (0.48) | GPR119CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL30187253 | 0.87 | GPR119 (0.43) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL24756985 | 0.85 | KDM4E (0.42) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL21456251 | 0.85 | SCN9A (0.46) | GPR119 | |
| SCHEMBL24461317 | 0.84 | TRPV3 (0.45) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL21673835 | 0.83 | GPR119 (0.42) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL25306862 | 0.82 | GPR119 (0.41) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL25309101 | 0.81 | GPR119 (0.51) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL25900331 | 0.80 | GPR119 (0.41) | GPR119NPC1ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026090330-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2026-04-30 | — | — | WO | disclosed |
| WO-2024220891-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2024-10-24 | — | — | WO | disclosed |
| WO-2023141570-A9 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF KRAS | ARVINAS OPERATIONS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| WO-2023141570-A2 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF KRAS | ARVINAS OPERATIONS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |