Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.52 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2726850 | 0.84 | MEN1 (0.65) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL11729468 | 0.83 | NPC1 (0.58) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL2269809 | 0.83 | NPC1 (0.69) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL27792368 | 0.80 | KCNMA1 (0.74) | NPC1RAB9AMEN1KMT2AKDM4E | |
| 2-Aminopyridine SCHEMBL9806564 | 0.76 | NPC1 (0.60) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL25900021 | 0.76 | SMN1; SMN2 (0.52) | NPC1RAB9ARXFP1KDM4EL3MBTL1 | |
| SCHEMBL9725157 | 0.76 | NPC1 (0.68) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL31175268 | 0.75 | MEN1 (0.53) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL31175266 | 0.75 | MEN1 (0.53) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL20610223 | 0.75 | SORT1 (0.68) | NPC1RAB9AMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215524-A1 | COMPOUND SERVING AS THYROID HORMONE BETA RECEPTOR AGONIST AND USES OF COMPOUND | Sunshine Lake Pharma Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |