Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30858342 | 0.88 | L3MBTL1 (0.57) | USP30L3MBTL1MAPTCYP3A4CYP2C19 | |
| SCHEMBL354815 | 0.88 | L3MBTL1 (0.57) | USP30L3MBTL1MAPTCYP3A4CYP2C19 | |
| SCHEMBL25313895 | 0.82 | CYP3A4 (0.58) | PKMMAPTCYP3A4CYP2C19CYP1A2 | |
| SCHEMBL30014462 | 0.81 | ALDH1A1 (0.50) | HDAC1L3MBTL1MAPTCYP2C19MEN1 | |
| SCHEMBL30796039 | 0.81 | L3MBTL1 (0.59) | USP30L3MBTL1MAPTHSD17B10MEN1 | |
| SCHEMBL29772849 | 0.80 | CYP11B2 (0.48) | HDAC2HDAC1USP30CYP3A4PARP1 | |
| SCHEMBL24628355 | 0.80 | CYP11B2 (0.48) | HDAC2HDAC1USP30CYP3A4PARP1 | |
| SCHEMBL24994418 | 0.79 | HDAC2 (0.45) | HDAC2HDAC1USP30PKMCYP11B2 | |
| SCHEMBL28615043 | 0.79 | PKM (0.45) | HDAC2HDAC1PKMMAPTCYP3A4 | |
| SCHEMBL24628132 | 0.79 | CYP11B2 (0.50) | HDAC2HDAC1USP30CYP3A4PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125486-A1 | SOMATOSTATIN RECEPTOR SUBTYPE 5 ANTAGONISTS, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 中国科学院上海药物研究所 | 2023-07-06 | — | — | WO | disclosed |