Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 2/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | MAP2 | P11137 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11190636 | 0.87 | DAO (0.60) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9384667 | 0.81 | KDM4E (0.63) | FLT3PDGFRB | |
| SCHEMBL8924352 | 0.81 | DAO (0.62) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11187166 | 0.81 | DAO (0.57) | FLT3DAOCSF1RGRIN2DGRIN3B | |
| SCHEMBL8987358 | 0.80 | ALDH1A1 (0.59) | CA2FLT3PDGFRB | |
| SCHEMBL25904140 | 0.78 | PRKAB2 (0.50) | CA1CA2MAOBFLT3PDGFRB | |
| SCHEMBL22719039 | 0.77 | MAOB (0.43) | CA1CA2MAOBADORA3ADORA1 | |
| SCHEMBL8925620 | 0.77 | DAO (0.49) | FLT3PDGFRBDAOMAP2GRIN2D | |
| SCHEMBL3732166 | 0.75 | FLT3 (0.48) | CA1CA2MAOBFLT3PDGFRB | |
| SCHEMBL831121 | 0.74 | PDGFRB (0.45) | CA2FLT3PDGFRBADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4006148-A | Carbostyril derivatives used as coccidiostats | IMC CHEMICAL GROUP, INC. (US) | 1977-02-01 | — | — | US | claimed |
| US-5614532-A | NERVOUS SYSTEM DISORDERS USING N-METHYLASPARTATE ANTAGONIST | MERCK, SHARP & DOHME LTD. (GB) | 1997-03-25 | — | — | US | disclosed |
| US-4395414-A | Substituted quinolinone-alkanecarboxylic acids and medicaments containing them, having a hyperglycaemic action | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-07-26 | — | — | US | disclosed |
| EP-0024638-A1 | Substituted quinolinone-alkanecarboxylic acids, their preparation, and medicaments containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1981-03-11 | — | — | EP | disclosed |
| WO-1981000564-A1 | SUBSTITUTED QUINOLINONE-ALKANECARBOXYLIC ACIDS,THEIR PREPARATION AND USE,AND MEDICAMENTS CONTAINING THEM | BYK GULDEN LOMBERG CHEM FAB (DE) | 1981-03-05 | — | — | WO | disclosed |