SCHEMBL2590584

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2578706	0.83	PDE5A (0.41)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL2461065	0.82	KDM4E (0.40)	GPR84KDR
	SCHEMBL2461306	0.82	IMPDH2 (0.40)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL2584806	0.82	NQO2 (0.41)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL2521643	0.81	CCNE1 (0.35)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL1136225	0.80	CCNE1 (0.34)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL2586806	0.80	NQO2 (0.37)	NQO2GPR84SLC6A9PDE5AMAOB
	SCHEMBL2575816	0.79	KDM4E (0.36)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL2465486	0.79	KDM4E (0.38)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL2462773	0.78	BTK (0.39)	PDE5AMEN1KMT2APLA2G1BHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.