SCHEMBL2461306

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2461065	0.82	KDM4E (0.40)	GPR84MAPTALDH1A1SMN1; SMN2ADORA3
	SCHEMBL2590584	0.82	TUBB4A (0.39)	IMPDH2TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL1136274	0.80	ALDH1A1 (0.33)	IMPDH2TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL2461172	0.80	IMPDH2 (0.42)	IMPDH2GPR84PDE5AALDH1A1SMN1; SMN2
	SCHEMBL2578706	0.79	PDE5A (0.41)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL2462773	0.78	BTK (0.39)	BTKPDE5AKMT2AMEN1MAPT
	SCHEMBL2462987	0.73	BTK (0.40)	GPR84BTKPDE5AKMT2AMEN1
	SCHEMBL2462928	0.71	PDE5A (0.41)	PDE5A
	SCHEMBL2430464	0.70	CNR2 (0.42)	PDE5AKMT2AMEN1MAPTALDH1A1
	SCHEMBL8313420	0.68	CDK8 (0.64)	CDK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.