SCHEMBL25907127

SCHEMBL25907127

CCCCC(CCCC)CCCCCCCCC(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
ALDH1A1 P00352 3/20 0.39
TDP1 Q9NUW8 1/20 0.39
DNM1 Q05193 2/20 0.39
CYP3A4 P08684 2/20 0.38
TSHR P16473 2/20 0.38
CA2 P00918 3/20 0.38
FDPS P14324 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.32
ACACB O00763 1/20 0.32
ACACA Q13085 1/20 0.32
MAPK1 P28482 1/20 0.32
OPRM1 P35372 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29876157 0.95 LMNA (0.50) LMNAALDH1A1DNM1TSHRCA2
SCHEMBL6011957 0.82 FDPS (0.41) LMNADNM1CA2FDPSACACB
SCHEMBL30483471 0.82 ACACB (0.52) CA2ACACBACACA
SCHEMBL8897199 0.82 ACACB (0.52) CA2ACACBACACA
SCHEMBL20568504 0.81 ALDH1A1 (0.56) LMNAALDH1A1TDP1CYP3A4TSHR
SCHEMBL31521566 0.81 ALDH1A1 (0.39) LMNAALDH1A1TDP1DNM1CYP3A4
SCHEMBL31521574 0.81 ACE2 (0.41) LMNADNM1CYP3A4CA2FDPS
SCHEMBL11698236 0.79 OPRM1 (0.41) LMNADNM1TSHRCA2FDPS
SCHEMBL10268276 0.79 ACACB (0.48) CA2FDPSACACBACACAMAPK1
SCHEMBL24981778 0.79 LMNA (0.65) LMNAALDH1A1TDP1DNM1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4215188-A1 AN AMINO LIPID, PREPARATION METHOD AND APPLICATION THEREOF Shenzhen MagicRNA Biotechnology Co., Ltd. (CN) 2023-07-26 EP disclosed