Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CRHBP | P24387 | 2/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.37 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.37 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27113243 | 0.78 | PRMT6 (0.47) | PRMT6HTTNPC1RAB9AMCL1 | |
| SCHEMBL17340934 | 0.72 | L3MBTL3 (0.45) | PRMT6HTTNPC1RAB9AMCL1 | |
| SCHEMBL8276471 | 0.71 | L3MBTL3 (0.47) | PRMT6HTTNPC1RAB9AMCL1 | |
| SCHEMBL14172860 | 0.69 | RAB9A (0.51) | PRMT6NPC1RAB9AMCL1LMNA | |
| SCHEMBL25497793 | 0.69 | L3MBTL3 (0.45) | PRMT6NPC1RAB9AMCL1L3MBTL1 | |
| SCHEMBL12367104 | 0.68 | PRMT6 (0.46) | PRMT6NPC1RAB9AMCL1L3MBTL1 | |
| SCHEMBL28156586 | 0.68 | PRMT6 (0.64) | PRMT6LMNAROCK2ROCK1MEN1 | |
| SCHEMBL24685615 | 0.68 | L3MBTL3 (0.45) | PRMT6L3MBTL1MBTD1TP53BP1L3MBTL3 | |
| SCHEMBL13920443 | 0.67 | PRMT6 (0.45) | PRMT6HTTLMNAROCK2ROCK1 | |
| SCHEMBL22144478 | 0.66 | SMN1; SMN2 (0.46) | PRMT6NPC1RAB9AMCL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4218752-A1 | MARKER FOR DETERMINING ANTI-CANCER EFFECTS OF MITOCHONDRIAL OXIDATIVE PHOSPHORYLATION PATHWAY INHIBITOR | Nanjing Shijiang Medicine Technology Co., Ltd (CN) | 2023-08-02 | — | — | EP | disclosed |