SCHEMBL27113243

SCHEMBL27113243

CC1CCN(c2cccc(CNC(=N)N)c2)CC1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PRMT6 Q96LA8 1/20 0.47
▸ HTT P42858 2/20 0.42
▸ ITGB3 P05106 1/20 0.42
▸ ITGA2B P08514 1/20 0.42
▸ NPC1 O15118 1/20 0.42
▸ RAB9A P51151 1/20 0.42
▸ MCL1 Q07820 1/20 0.42
▸ LMNA P02545 3/20 0.40
▸ CRHBP P24387 2/20 0.40
▸ CRHR2 Q13324 2/20 0.40
▸ KLKB1 P03952 2/20 0.40
▸ KLK1 P06870 2/20 0.40
▸ MBTD1 Q05BQ5 1/20 0.40
▸ TP53BP1 Q12888 1/20 0.40
▸ L3MBTL3 Q96JM7 1/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.40
▸ TRPV1 Q8NER1 1/20 0.39
▸ AGXT P21549 2/20 0.39
▸ MEN1 O00255 3/20 0.39
▸ KMT2A Q03164 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27113249 0.84 AGXT (0.57) PRMT6HTTITGB3ITGA2BLMNA
SCHEMBL27114131 0.82 ITGB3 (0.46) PRMT6HTTITGB3ITGA2BLMNA
SCHEMBL27113244 0.82 HTR7 (0.49) PRMT6HTTITGB3ITGA2BMAPT
SCHEMBL27120294 0.81 PRMT6 (0.46) PRMT6HTTITGB3ITGA2BLMNA
SCHEMBL27113417 0.81 PRMT6 (0.46) PRMT6HTTITGB3ITGA2BLMNA
SCHEMBL27118870 0.79 PRMT6 (0.46) PRMT6HTTITGB3ITGA2BLMNA
SCHEMBL27114252 0.78 PRMT6 (0.43) PRMT6HTTITGB3ITGA2BLMNA
SCHEMBL25907880 0.78 PRMT6 (0.43) PRMT6HTTNPC1RAB9AMCL1
SCHEMBL8276471 0.78 L3MBTL3 (0.47) PRMT6HTTNPC1RAB9AMCL1
SCHEMBL27113245 0.75 SMN1; SMN2 (0.53) HTTITGB3ITGA2BLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240066135-A1 DRUG CONJUGATES AND USES THEREOF SUPERTRANS MEDICAL LTD (IL) 2024-02-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240066135-A1 DRUG CONJUGATES AND USES THEREOF SLC7A1, ABCB11, SLC1A5 PRMT6 1447/4885HTT 1812/4885ITGB3 475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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