Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23241820 | 0.84 | PPARD (0.39) | CYP1A2CYP2C9CYP2C19MRGPRX4L3MBTL1 | |
| SCHEMBL513210 | 0.83 | IDO1 (0.48) | CYP1A2CYP2C9CYP2C19MRGPRX4L3MBTL1 | |
| SCHEMBL29852434 | 0.83 | ANO1 (0.45) | MRGPRX4L3MBTL1GAAALDH1A1POLB | |
| SCHEMBL23218135 | 0.83 | ANO1 (0.45) | MRGPRX4L3MBTL1GAAALDH1A1POLB | |
| SCHEMBL23229180 | 0.81 | TBXAS1 (0.43) | CYP1A2CYP2C9CYP2C19ALDH1A1POLB | |
| SCHEMBL24651096 | 0.81 | POLB (0.45) | CYP1A2CYP2C9CYP2C19L3MBTL1GAA | |
| SCHEMBL21561992 | 0.81 | NLRP3 (0.42) | CYP1A2CYP2C9CYP2C19L3MBTL1ALDH1A1 | |
| SCHEMBL29886373 | 0.81 | LIPG (0.46) | CYP2C19MRGPRX4ALDH1A1PPARGPPARA | |
| SCHEMBL24651099 | 0.81 | POLB (0.42) | CYP1A2CYP2C9CYP2C19L3MBTL1GAA | |
| SCHEMBL21223098 | 0.79 | CYP2C19 (0.51) | CYP1A2CYP2C9CYP2C19MBOAT4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11708347-B2 | Substituted benzofuran, benzopyrrole, benzothiophene, and structurally related complement inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 2023-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11708347-B2 | Substituted benzofuran, benzopyrrole, benzothiophene, and structurally related complement inhibitors | C9, C5, C1QBP | CYP1A2 170/4885CYP2C9 200/4885CYP2C19 67/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.