Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 5/20 | 0.51 |
| ▸ | CTSS | P25774 | 5/20 | 0.46 |
| ▸ | CTSK | P43235 | 5/20 | 0.46 |
| ▸ | CTSB | P07858 | 3/20 | 0.46 |
| ▸ | BRD4 | O60885 | 3/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5264017 | 0.89 | GLS (0.51) | GLSCTSSCTSKCTSBBRD4 | |
| SCHEMBL5261267 | 0.89 | GLS (0.51) | GLSCTSSCTSKCTSBBRD4 | |
| SCHEMBL25968478 | 0.87 | GLS (0.49) | GLSCTSSCTSKCTSBBRD4 | |
| SCHEMBL5263829 | 0.85 | CTSS (0.47) | GLSCTSSCTSKCTSBBRD4 | |
| SCHEMBL21089822 | 0.84 | GLS (0.48) | GLSCTSKBRD4KDM4ACREBBP | |
| SCHEMBL28637112 | 0.84 | GLS (0.48) | GLSCTSKBRD4KDM4ACREBBP | |
| SCHEMBL12407064 | 0.84 | GLS (0.47) | GLSCTSSCTSKCTSBBRD4 | |
| SCHEMBL12645129 | 0.83 | SLC7A5 (0.64) | GLSCTSSCTSKCTSBSLC7A5 | |
| SCHEMBL13821569 | 0.83 | GLS (0.48) | GLSCTSSCTSKCTSBBRD4 | |
| SCHEMBL19143295 | 0.83 | SLC7A5 (0.64) | GLSCTSSCTSKCTSBSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11708347-B2 | Substituted benzofuran, benzopyrrole, benzothiophene, and structurally related complement inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 2023-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11708347-B2 | Substituted benzofuran, benzopyrrole, benzothiophene, and structurally related complement inhibitors | C9, C5, C1QBP | GLS 308/4885CTSS 305/4885CTSK 1238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.