Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 6/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | NCF1 | P14598 | 4/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | CYBB | P04839 | 1/20 | 0.33 |
| ▸ | NOX5 | Q96PH1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18467076 | 0.88 | HSP90AB1 (0.38) | DGAT1HSP90AB1NCF1MMP2MMP9 | |
| SCHEMBL12092344 | 0.85 | NOTUM (0.41) | DGAT1HSP90AB1CYP19A1GGPS1 | |
| SCHEMBL12033272 | 0.84 | DGAT1 (0.47) | DGAT1HSP90AB1CYP19A1NCF1CYBB | |
| SCHEMBL12033268 | 0.84 | DGAT1 (0.53) | DGAT1HSP90AB1NCF1ABCC1ABCG2 | |
| SCHEMBL24016423 | 0.84 | HSP90AB1 (0.39) | DGAT1HSP90AB1CYP19A1NCF1GGPS1 | |
| SCHEMBL12092336 | 0.83 | GGPS1 (0.41) | CYP19A1GGPS1 | |
| SCHEMBL20670747 | 0.83 | HSP90AB1 (0.40) | DGAT1HSP90AB1CYP19A1GGPS1 | |
| SCHEMBL20650987 | 0.83 | P2RX7 (0.47) | HSP90AB1CYP19A1GGPS1 | |
| SCHEMBL12092354 | 0.82 | DGAT1 (0.42) | DGAT1HSP90AB1MMP2MMP9MMP8 | |
| SCHEMBL12092365 | 0.82 | DGAT1 (0.42) | DGAT1HSP90AB1MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219933-A1 | STERICALLY SHIELDED HEPTAMETHINE CYANINE DYES | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219933-A1 | STERICALLY SHIELDED HEPTAMETHINE CYANINE DYES | FCGR3B, MYADM, FCGR2A | DGAT1 4636/4885HSP90AB1 3844/4885CYP19A1 4080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.