Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20650987 | 0.87 | P2RX7 (0.47) | HSP90AB1CYP19A1P2RX7ALOX5GGPS1 | |
| SCHEMBL24016423 | 0.85 | HSP90AB1 (0.39) | HSP90AB1CYP19A1P2RX7ALOX5LOXL2 | |
| SCHEMBL12092344 | 0.83 | NOTUM (0.41) | HSP90AB1CYP19A1ALOX5LOXL2GGPS1 | |
| SCHEMBL18467076 | 0.83 | HSP90AB1 (0.38) | HSP90AB1ALOX5DGAT1 | |
| SCHEMBL25908962 | 0.83 | DGAT1 (0.46) | HSP90AB1CYP19A1GGPS1DGAT1 | |
| SCHEMBL20650985 | 0.81 | CYP19A1 (0.36) | HSP90AB1CYP19A1ALOX5LOXL2GGPS1 | |
| SCHEMBL15257082 | 0.79 | APP (0.39) | HSP90AB1ALOX5APPDGAT1 | |
| SCHEMBL17678394 | 0.78 | GGPS1 (0.37) | CYP19A1GGPS1 | |
| SCHEMBL12092365 | 0.77 | DGAT1 (0.42) | HSP90AB1ALOX5DGAT1 | |
| SCHEMBL12092354 | 0.77 | DGAT1 (0.42) | HSP90AB1ALOX5DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190023732-A1 | OLIGONUCLEOTIDES | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2019-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190023732-A1 | OLIGONUCLEOTIDES | NSUN3, DCLRE1B, TRDMT1 | HSP90AB1 2714/4885CYP19A1 4817/4885P2RX7 784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.