SCHEMBL2590938

SCHEMBL2590938

O=c1[nH]cc(O)c(O)c1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.48
DAO P14920 8/20 0.44
ERCC1 P07992 3/20 0.44
ERCC4 Q92889 3/20 0.44
BCL2 P10415 1/20 0.36
MCL1 Q07820 1/20 0.36
ADRA1A P35348 1/20 0.34
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
MAPT P10636 2/20 0.34
PKM P14618 2/20 0.34
MEN1 O00255 1/20 0.34
CYP1A2 P05177 1/20 0.34
POLB P06746 1/20 0.34
CYP2D6 P10635 1/20 0.34
THRB P10828 1/20 0.34
CYP2C9 P11712 1/20 0.34
MAPK1 P28482 1/20 0.34
CYP2C19 P33261 1/20 0.34
CASP6 P55212 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31160182 0.65 PARP1 (0.59) GAADAOERCC1ERCC4KDM4E
SCHEMBL1264071 0.65 PARP1 (0.59) GAADAOERCC1ERCC4KDM4E
SCHEMBL48366 0.65
SCHEMBL16654461 0.64 DAO (0.42) GAADAOERCC1ERCC4KDM4E
SCHEMBL2116156 0.63
SCHEMBL5175749 0.63
SCHEMBL13674924 0.62 PARP1 (0.46) GAADAOERCC1ERCC4ADRA1A
SCHEMBL13760002 0.62
SCHEMBL10895825 0.62
SCHEMBL12420716 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118785925-A Marker precursors and radiotracers with three or more targeting vectors for use in diagnostic nuclear medicine therapies 原子治疗有限公司 2024-10-15 CN claimed
CN-117642190-A Dimer-labeled precursor conjugated with a three-linker and radiotracer derived therefrom 梅迪阿内泽有限公司 2024-03-01 CN claimed
CN-116916972-A Marker precursors and radiotracers for use in nuclear medicine diagnosis and treatment of prostate cancer-induced bone metastases SCV-特种化学品销售有限公司 2023-10-20 CN claimed
EP-4168173-A1 MICROWAVE DEVICE FOR THE RAPID LABELLING OF IN KIT-FORMULATED RADIOPHARMACEUTICALS C.M.S. S.p.A. (IT) 2023-04-26 EP claimed
CN-114980931-A Intelligent drug delivery system and kit for nuclear medicine cytotoxicity dual therapy diagnosis SCV-特种化学品销售有限公司 2022-08-30 CN claimed
WO-2021234741-A1 MICROWAVE DEVICE FOR THE RAPID LABELLING OF IN KIT-FORMULATED RADIOPHARMACEUTICALS C.M.S. S.P.A. (IT) 2021-11-25 WO claimed
EP-3452436-B1 IN-KIT PREPARATION OF GALLIUM-68 LABELLED RADIOPHARMACEUTICALS GAMMA SERVIZI S R L (IT) 2021-10-13 EP claimed
CN-113164630-A Mark precursors with squaric acid linkage SCV-特种化学品销售有限公司 2021-07-23 CN claimed
EP-3452436-A2 IN-KIT PREPARATION OF GALLIUM-68 LABELLED RADIOPHARMACEUTICALS Azienda USL di Reggio Nell' Emilia (IT) 2019-03-13 EP claimed
CN-118785925-A Marker precursors and radiotracers with three or more targeting vectors for use in diagnostic nuclear medicine therapies 原子治疗有限公司 2024-10-15 CN disclosed
CN-117642190-A Dimer-labeled precursor conjugated with a three-linker and radiotracer derived therefrom 梅迪阿内泽有限公司 2024-03-01 CN disclosed
CN-114796533-B Marking precursors with squaric acid linkages SCV-特种化学品销售有限公司 2024-01-26 CN disclosed
CN-116916972-A Marker precursors and radiotracers for use in nuclear medicine diagnosis and treatment of prostate cancer-induced bone metastases SCV-特种化学品销售有限公司 2023-10-20 CN disclosed
EP-4168173-A1 MICROWAVE DEVICE FOR THE RAPID LABELLING OF IN KIT-FORMULATED RADIOPHARMACEUTICALS C.M.S. S.p.A. (IT) 2023-04-26 EP disclosed
EP-2637705-B1 CONJUGATES AND THEIR USES IN MOLECULAR IMAGING KING S COLLEGE LONDON (GB) 2017-03-29 EP disclosed
US-20160358683-A1 PROCESS FOR PRODUCING GALLIUM-68 THROUGH THE IRRADIATION OF A SOLUTION TARGET ION BEAM APPLICATIONS 2016-12-08 US disclosed
EP-3101660-A1 PROCESS FOR PRODUCING GALLIUM-68 THROUGH THE IRRADIATION OF A SOLUTION TARGET Universidade de Coimbra (PT) 2016-12-07 EP disclosed
US-20130157375-A1 COMPOUND LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE (GB) 2013-06-20 US disclosed
EP-2564205-A1 COMPOUND King's College London (GB) 2013-03-06 EP disclosed
WO-2011135361-A1 COMPOUND KING'S COLLEGE LONDON (GB) 2011-11-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130157375-A1 COMPOUND TFRC, FTH1, SLC40A1 GAA 2487/4885DAO 2561/4885ERCC1 2954/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.