Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1867904 | 0.87 | NLRP3 (0.54) | ALDH1A1POLBNLRP3KDM4EL3MBTL1 | |
| SCHEMBL12023029 | 0.86 | NLRP3 (0.50) | ALDH1A1POLBNLRP3KDM4EL3MBTL1 | |
| SCHEMBL23425650 | 0.81 | CA12 (0.50) | ALDH1A1POLBNLRP3KDM4EL3MBTL1 | |
| SCHEMBL12000324 | 0.80 | NLRP3 (0.48) | ALDH1A1POLBNLRP3KDM4EL3MBTL1 | |
| SCHEMBL3622900 | 0.80 | NLRP3 (0.48) | ALDH1A1POLBNLRP3KDM4EL3MBTL1 | |
| SCHEMBL13185298 | 0.80 | NLRP3 (0.48) | ALDH1A1POLBNLRP3KDM4EL3MBTL1 | |
| SCHEMBL5252336 | 0.80 | KMT2A (0.60) | ALDH1A1POLBKDM4EKMT2AMEN1 | |
| SCHEMBL11960791 | 0.80 | NLRP3 (0.48) | ALDH1A1POLBNLRP3KDM4EL3MBTL1 | |
| SCHEMBL29943508 | 0.80 | KMT2A (0.60) | ALDH1A1POLBKDM4EKMT2AMEN1 | |
| SCHEMBL7494802 | 0.79 | NLRP3 (0.42) | ALDH1A1NLRP3KDM4EL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11708347-B2 | Substituted benzofuran, benzopyrrole, benzothiophene, and structurally related complement inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 2023-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11708347-B2 | Substituted benzofuran, benzopyrrole, benzothiophene, and structurally related complement inhibitors | C9, C5, C1QBP | ALDH1A1 1047/4885POLB 3620/4885NLRP3 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.