SCHEMBL25909635

SCHEMBL25909635

Cc1ccc(CCC[SiH](c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.44
DRD4 P21917 1/20 0.44
DRD3 P35462 1/20 0.44
TDP1 Q9NUW8 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
PLAAT3 P53816 1/20 0.41
PLAAT5 Q96KN8 1/20 0.41
PLAAT2 Q9NWW9 1/20 0.41
PLAAT4 Q9UL19 1/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2A6 P11509 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
KCNH2 Q12809 2/20 0.41
IGF1R P08069 1/20 0.41
ALOX15 P16050 1/20 0.41
CNR2 P34972 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25909607 0.89 CYP1A2 (0.43) DRD2DRD4DRD3TDP1L3MBTL1
SCHEMBL2454765 0.86 SIGMAR1 (0.46) L3MBTL1ALOX15ALDH1A1MAOBHTR2A
SCHEMBL28444995 0.81 LMNA (0.43) DRD2DRD3TAAR1KCNH2ALDH1A1
SCHEMBL28443876 0.81 TAAR1 (0.41) L3MBTL1PLAAT3PLAAT5PLAAT2PLAAT4
SCHEMBL25909648 0.80 MAOA (0.50) L3MBTL1IGF1RALOX15MAOBHTR2A
SCHEMBL28435831 0.79 SIGMAR1 (0.50) L3MBTL1MAOB
SCHEMBL6546824 0.78 MAOB (0.60) DRD2DRD4DRD3TDP1L3MBTL1
SCHEMBL2356590 0.78 HTR2A (0.60) DRD2DRD4DRD3TDP1L3MBTL1
SCHEMBL6546801 0.76 MAOB (0.58) TDP1L3MBTL1IGF1RALOX15MAOB
P-Xylene SCHEMBL20836571 0.75 HTR2A (0.56) TDP1L3MBTL1CYP1A2ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230241597-A1 PLATFORM FOR THE RECOVERY OF TRANSITION METAL CATALYSTS TEXAS TECH UNIVERSITY SYSTEM 2023-08-03 US disclosed
CN-111393466-A Gem disilicon compound, preparation method and application thereof 南开大学 2020-07-10 CN disclosed