SCHEMBL25909648

SCHEMBL25909648

c1ccc(CCCC[SiH](c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.50
MAOB P27338 2/20 0.48
SIGMAR1 Q99720 10/20 0.47
L3MBTL1 Q9Y468 1/20 0.45
MAPT P10636 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
HTR2A P28223 1/20 0.43
IGF1R P08069 1/20 0.42
ALOX15 P16050 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28435831 0.98 SIGMAR1 (0.50) MAOAMAOBSIGMAR1L3MBTL1MAPT
SCHEMBL2454765 0.93 SIGMAR1 (0.46) MAOAMAOBSIGMAR1L3MBTL1HTR2A
SCHEMBL703363 0.86 HTR2A (0.32) MAPTHTR2A
SCHEMBL706873 0.81 CALM1 (0.38) MAPTHTR2A
SCHEMBL28443876 0.80 TAAR1 (0.41) MAOBSIGMAR1L3MBTL1MAPTHTR2A
SCHEMBL28444995 0.80 LMNA (0.43) MAOBHTR2A
SCHEMBL451456 0.78 MAOA (0.74) MAOAMAOBSIGMAR1L3MBTL1MAPT
SCHEMBL10608209 0.76 MAOA (0.52) MAOAMAOBSIGMAR1L3MBTL1MAPT
SCHEMBL707928 0.76 MAOA (0.52) MAOAMAOBSIGMAR1L3MBTL1MAPT
SCHEMBL705290 0.76 MAOA (0.52) MAOAMAOBSIGMAR1L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230241597-A1 PLATFORM FOR THE RECOVERY OF TRANSITION METAL CATALYSTS TEXAS TECH UNIVERSITY SYSTEM 2023-08-03 US disclosed
CN-112387313-B Tridentate phenanthroline manganese catalyst and application thereof in synthesis of organic silicon/boron compound 中山大学 2022-08-16 CN disclosed
CN-112387313-A Tridentate phenanthroline manganese catalyst and application thereof in synthesis of organic silicon/boron compound 中山大学 2021-02-23 CN disclosed