Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 17/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 9/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.49 |
| ▸ | FLT3 | P36888 | 5/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25910292 | 0.85 | CSF1R (0.57) | CSF1RPDGFRAPDGFRBFLT3KDR | |
| SCHEMBL25910409 | 0.84 | CSF1R (0.56) | CSF1RPDGFRAPDGFRBFLT3KDR | |
| SCHEMBL25910294 | 0.80 | CSF1R (0.55) | CSF1RPDGFRAPDGFRBFLT3SCN9A | |
| SCHEMBL25910295 | 0.72 | SCN9A (0.34) | CSF1RPDGFRAPDGFRBSCN9A | |
| SCHEMBL25910179 | 0.71 | CSF1R (0.37) | CSF1RPDGFRAPDGFRBFLT3KDR | |
| SCHEMBL25910429 | 0.71 | KDM4E (0.38) | SCN9A | |
| SCHEMBL25910298 | 0.70 | CSF1R (0.75) | CSF1RPDGFRAPDGFRBFLT3KDR | |
| SCHEMBL25910565 | 0.70 | CSF1R (0.79) | CSF1RPDGFRAPDGFRBKDR | |
| SCHEMBL25910028 | 0.70 | CSF1R (0.53) | CSF1RPDGFRAPDGFRBFLT3KDR | |
| SCHEMBL25910288 | 0.69 | CSF1R (0.41) | CSF1RPDGFRAPDGFRBFLT3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |