Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | HPGD | P15428 | 3/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14820402 | 0.87 | ALDH1A1 (0.58) | ALDH1A1HPGDHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL18932089 | 0.85 | ALDH1A1 (0.55) | ALDH1A1HPGDHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL10624038 | 0.84 | ALDH1A1 (0.77) | ALDH1A1HPGDHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL436153 | 0.78 | ALDH1A1 (0.63) | ALDH1A1HPGDHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL16809191 | 0.76 | ALDH1A1 (0.58) | ALDH1A1HPGDHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL10694441 | 0.76 | KDM4E (0.65) | ALDH1A1HPGDHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL25912269 | 0.75 | MAPT (0.46) | ALDH1A1HPGDHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL521212 | 0.75 | MAPT (0.97) | ALDH1A1HPGDHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL1887466 | 0.75 | ALDH1A1 (0.63) | ALDH1A1HPGDHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL8502461 | 0.75 | HPGD (0.51) | ALDH1A1HPGDHSD17B10CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11420976-B2 | Heterocyclic compounds as anti-viral agents | ENANTA PHARMACEUTICALS, INC. (US) | 2022-08-23 | — | — | US | disclosed |
| US-20210238188-A1 | HETEROCYCLIC COMPOUNDS AS ANTI-VIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238188-A1 | HETEROCYCLIC COMPOUNDS AS ANTI-VIRAL AGENTS | VIP, ACE, FURIN | ALDH1A1 1686/4885HPGD 36/4885HSD17B10 1288/4885 |
| US-11420976-B2 | Heterocyclic compounds as anti-viral agents | VIP, ACE, FURIN | ALDH1A1 1686/4885HPGD 36/4885HSD17B10 1288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.