Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | LTK | P29376 | 1/20 | 0.32 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22216371 | 0.72 | DRD2 (0.34) | CCNA2CDK2CCNA1PSEN1PSEN2 | |
| SCHEMBL4371798 | 0.66 | KCNH2 (0.38) | MAPK1PIK3CGKCNH2IDH1P2RX3 | |
| SCHEMBL24810222 | 0.66 | P2RX3 (0.32) | KCNH2IDH1P2RX3 | |
| SCHEMBL23798276 | 0.66 | POLB (0.36) | CCNA2CDK2CCNA1PSEN1PSEN2 | |
| SCHEMBL3640565 | 0.64 | KCNH2 (0.34) | PIK3CGKCNH2ALDH1A1IDH1P2RX3 | |
| SCHEMBL31060463 | 0.64 | KCNH2 (0.34) | PIK3CGKCNH2ALDH1A1IDH1P2RX3 | |
| SCHEMBL9259806 | 0.64 | IDH1 (0.43) | KCNH2XIAPKDM4EALDH1A1HSD17B10 | |
| SCHEMBL9252905 | 0.64 | IDH1 (0.40) | KCNH2XIAPKDM4EALDH1A1HSD17B10 | |
| SCHEMBL23336558 | 0.63 | GRM5 (0.40) | CCNA2CDK2CCNA1DRD2ALDH1A1 | |
| SCHEMBL12386590 | 0.63 | AADAT (0.40) | KCNH2IDH1P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219495-A1 | AHR MODULATORS | Ideaya Biosciences, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |