Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | HCK | P08631 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3640565 | 1.00 | KCNH2 (0.34) | KCNH2P2RX3ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL21676756 | 0.77 | CDC25B (0.34) | CYP1A2CYP3A4GABRG2GABRB3GABRA5 | |
| SCHEMBL4371798 | 0.74 | KCNH2 (0.38) | KCNH2P2RX3CYP2C9IDH1GRM5 | |
| SCHEMBL16478074 | 0.74 | KCNH2 (0.38) | KCNH2P2RX3IDH1GRM5GRM1 | |
| SCHEMBL29620470 | 0.73 | ADAM17 (0.34) | IDH1GABRG2GABRB3GABRA5GRM5 | |
| SCHEMBL9252869 | 0.73 | ADAM17 (0.45) | P2RX3ALDH1A1IDH1GRM5GRM1 | |
| SCHEMBL3640566 | 0.71 | LMNA (0.39) | ALDH1A1GABRG2GABRB3GABRA5GRM5 | |
| SCHEMBL9259806 | 0.70 | IDH1 (0.43) | KCNH2ALDH1A1CYP3A4IDH1GRM5 | |
| SCHEMBL12386590 | 0.69 | AADAT (0.40) | KCNH2P2RX3IDH1GRM5GRM1 | |
| SCHEMBL24810222 | 0.68 | P2RX3 (0.32) | KCNH2P2RX3IDH1GRM5GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |