Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 2/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24848168 | 0.88 | MEN1 (0.46) | SCN1ASCN2ASCN3ASMN1; SMN2LMNA | |
| SCHEMBL5010378 | 0.88 | PARP10 (0.44) | SCN1ASCN2ASCN3ASMN1; SMN2LMNA | |
| SCHEMBL25920617 | 0.88 | LMNA (0.56) | SCN1ASCN2ASCN3ASMN1; SMN2LMNA | |
| SCHEMBL26804979 | 0.86 | RAB9A (0.46) | SCN1ASCN2ASCN3ASMN1; SMN2LMNA | |
| SCHEMBL5010823 | 0.86 | SMN1; SMN2 (0.49) | SCN1ASCN2ASCN3ASMN1; SMN2LMNA | |
| SCHEMBL24204876 | 0.85 | SCN1A (0.46) | SCN1ASCN2ASCN3ASMN1; SMN2LMNA | |
| SCHEMBL6057098 | 0.81 | SCN1A (0.69) | SCN1ASCN2ASCN3ASMN1; SMN2LMNA | |
| SCHEMBL12426775 | 0.79 | SCN1A (0.71) | SCN1ASCN2ASCN3ASMN1; SMN2LMNA | |
| SCHEMBL13225900 | 0.79 | TDP1 (0.59) | SMN1; SMN2LMNANPC1RAB9AHTT | |
| SCHEMBL6865989 | 0.78 | ACHE (0.41) | LMNACYP1A2NPC1RAB9ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215525-A1 | PIPERAZINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | Zhejiang Hisun Pharmaceutical Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |