Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1378229 | 0.81 | HPGD (0.38) | EPHX1LMNACYP2D6SLC6A2SLC6A3 | |
| SCHEMBL6874059 | 0.79 | MAOA (0.50) | TAS1R3TAS1R1LMNACYP2D6SLC6A2 | |
| SCHEMBL25913609 | 0.78 | SCN1A (0.48) | LMNACYP2D6CYP1A2MAPTCYP2C19 | |
| SCHEMBL1378233 | 0.78 | ALDH1A1 (0.45) | EPHX1LMNARAB9ANPC1 | |
| SCHEMBL24848168 | 0.77 | MEN1 (0.46) | EPHX1LMNACYP2D6CYP1A2MAPT | |
| SCHEMBL5010378 | 0.77 | PARP10 (0.44) | LMNACYP2D6CYP1A2MAPTRAB9A | |
| SCHEMBL25920617 | 0.77 | LMNA (0.56) | LMNACYP2D6CHRM2CYP1A2MAPT | |
| SCHEMBL1675118 | 0.76 | CA12 (0.53) | TAS1R3TAS1R1LMNATUBB4ATUBB | |
| SCHEMBL6614030 | 0.76 | TAS1R3 (0.51) | TAS1R3TAS1R1TUBB4ATUBBTUBA3C | |
| SCHEMBL6874334 | 0.76 | TAS1R3 (0.45) | TAS1R3TAS1R1TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451185-A1 | INDOLE-2-CARBOXAMIDES AS FACTOR XA INHIBITORS | Aventis Pharma Deutschland GmbH (DE) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003044014-A1 | INDOLE-2-CARBOXAMIDES AS FACTOR XA INHIBITORS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-05-30 | — | — | WO | disclosed |