SCHEMBL2591633

SCHEMBL2591633

CCCCCCCC/C=C\CCCCCCCC(=O)N(C(=O)CCCCCCC/C=C\CCCCCCCC)C(CO)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 4/20 0.54
PPARD Q03181 4/20 0.54
PPARA Q07869 4/20 0.54
TERT O14746 3/20 0.54
PTPN1 P18031 3/20 0.54
HSD17B10 Q99714 3/20 0.54
FABP4 P15090 3/20 0.54
F7 P08709 3/20 0.54
F3 P13726 3/20 0.54
MAPT P10636 2/20 0.54
BLM P54132 2/20 0.54
LMNA P02545 2/20 0.54
CYP1A2 P05177 2/20 0.54
ALOX15 P16050 2/20 0.54
CYP2C19 P33261 2/20 0.54
DUSP3 P51452 2/20 0.54
FAAH O00519 2/20 0.54
CYP19A1 P11511 2/20 0.54
PTGS1 P23219 2/20 0.54
NR4A2 P43354 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2591639 1.00 PPARG (0.54) PPARGPPARDPPARATERTPTPN1
SCHEMBL2591637 1.00 PPARG (0.54) PPARGPPARDPPARATERTPTPN1
SCHEMBL2591642 1.00 PPARG (0.54) PPARGPPARDPPARATERTPTPN1
Serine SCHEMBL28812093 0.92 TERT (0.47) PPARGPPARDPPARATERTPTPN1
SCHEMBL2235152 0.91 GPR84 (0.45) PPARGPPARDPPARAPTPN1HSD17B10
SCHEMBL28530662 0.91 GPR84 (0.45) PPARGPPARDPPARAPTPN1HSD17B10
SCHEMBL28530660 0.91 GPR84 (0.45) PPARGPPARDPPARAPTPN1HSD17B10
SCHEMBL2235149 0.91 GPR84 (0.45) PPARGPPARDPPARAPTPN1HSD17B10
SCHEMBL825632 0.91 GPR84 (0.45) PPARGPPARDPPARAPTPN1HSD17B10
SCHEMBL825631 0.91 GPR84 (0.45) PPARGPPARDPPARAPTPN1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114736925-A Circular mRNA vaccine development platform for cancer caused by virus infection 奥明(杭州)生物医药有限公司 2022-07-12 CN claimed
EP-2673000-B1 POLYMER-CARBOHYDRATE-LIPID CONJUGATES WU NIAN (US) 2018-05-16 EP disclosed
CN-104704023-B Polymer-carbohydrate-lipid conjugates 念·吴 2016-10-19 CN disclosed
US-9175027-B2 Polymer-carbohydrate-lipid conjugates LIPOSEUTICALS, INC. 2015-11-03 US disclosed
CN-104704023-A Polymer-carbohydrate-lipid conjugates WU NIAN 2015-06-10 CN disclosed
EP-2673000-A2 POLYMER-CARBOHYDRATE-LIPID CONJUGATES Wu, Nian (US) 2013-12-18 EP disclosed
WO-2012109112-A2 POLYMER-CARBOHYDRATE-LIPID CONJUGATES WU NIAN (US) 2012-08-16 WO disclosed
WO-2012109052-A1 POLYMER-CARBOHYDRATE-LIPID CONJUGATES WU NIAN (US) 2012-08-16 WO disclosed
US-20120202979-A1 POLYMER-CARBOHYDRATE-LIPID CONJUGATES LIPOSEUTICALS, INC. 2012-08-09 US disclosed
US-20120202890-A1 POLYMER-CARBOHYDRATE-LIPID CONJUGATES WU NIAN (US) 2012-08-09 US disclosed
WO-2011139343-A2 AMINO ACID LINKED PEG-LIPID CONJUGATES WU NIAN (US) 2011-11-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120202890-A1 POLYMER-CARBOHYDRATE-LIPID CONJUGATES LIPC, FUT6, UGCG PPARG 290/4885PPARD 371/4885PPARA 255/4885
US-20120202979-A1 POLYMER-CARBOHYDRATE-LIPID CONJUGATES LIPC, FUT6, UGCG PPARG 290/4885PPARD 371/4885PPARA 255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.