Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 9/20 | 0.47 |
| ▸ | LPL | P06858 | 8/20 | 0.47 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | P4HB | P07237 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25916638 | 0.85 | MAPT (0.34) | LIPGLPLDGAT1MAPTROCK1 | |
| SCHEMBL25916640 | 0.84 | ROCK1 (0.38) | LIPGLPLDGAT1MAPTROCK1 | |
| SCHEMBL16611970 | 0.74 | LIPG (0.51) | LIPGLPL | |
| SCHEMBL30613529 | 0.70 | ALDH1A1 (0.54) | LIPGLPLMAPT | |
| SCHEMBL26988951 | 0.70 | ALDH1A1 (0.54) | LIPGLPLMAPT | |
| SCHEMBL15867805 | 0.69 | LIPG (0.49) | LIPGLPL | |
| SCHEMBL13663767 | 0.67 | MAPT (0.40) | MAPT | |
| SCHEMBL13663770 | 0.67 | MAPT (0.40) | MAPT | |
| SCHEMBL10021061 | 0.67 | LIPG (1.00) | LIPGLPLDGAT1KEAP1NFE2L2 | |
| SCHEMBL476870 | 0.67 | LIPG (1.00) | LIPGLPLDGAT1KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139379-A1 | MODULATORS OF RHO-ASSOCIATED PROTEIN KINASE (ROCK) | REDX PHARMA PLC (GB) | 2023-07-27 | — | — | WO | disclosed |