SCHEMBL25916954

SCHEMBL25916954

CO[Si](CCCC(C)(CCC[Si](OC)(OC)OC)CNC(C)=O)(OC)OC

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
MAPK1 P28482 1/20 0.32
HIF1A Q16665 1/20 0.32
MTNR1A P48039 2/20 0.32
MTNR1B P49286 2/20 0.32
THRB P10828 1/20 0.31
PKM P14618 1/20 0.31
HTT P42858 1/20 0.30
PDCD1LG2 Q9BQ51 1/20 0.30
CD274 Q9NZQ7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25916946 0.84 KDM4E (0.33) KDM4EMAPK1HIF1AMTNR1AMTNR1B
SCHEMBL26476788 0.83 KDM4E (0.32) KDM4EMAPK1HIF1A
SCHEMBL25917043 0.79
SCHEMBL5415072 0.77 LMNA (0.38)
SCHEMBL14885197 0.76 PAOX (0.39) KDM4EMAPK1HIF1ATHRBPKM
SCHEMBL960689 0.74 KDM4E (0.56) KDM4EMAPK1HIF1AMTNR1AMTNR1B
SCHEMBL21712880 0.73 MEN1 (0.47) KDM4EMAPK1HIF1AHTT
SCHEMBL25916947 0.72 MTNR1A (0.30) MTNR1AMTNR1B
SCHEMBL25917045 0.72
SCHEMBL20781421 0.71 MEN1 (0.46) KDM4EMAPK1HIF1AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11873415-B2 Substrate with water repellent oil repellent layer, vapor deposition material, and method for producing substrate with water repellent oil repellent layer AGC Inc. (JP) 2024-01-16 US disclosed
US-20230220236-A1 COMPOSITION, SUBSTRATE WITH SURFACE LAYER, METHOD FOR PRODUCING SUBSTRATE WITH SURFACE LAYER, COMPOUNDS, AND METHODS FOR PRODUCING COMPOUNDS AGC Inc. (JP) 2023-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230220236-A1 COMPOSITION, SUBSTRATE WITH SURFACE LAYER, METHOD FOR PRODUCING SUBSTRATE WITH SURFACE LAYER, COMPOUNDS, AND METHODS FOR PRODUCING COMPOUNDS ZRANB2, ITGB1, ITGB2 KDM4E 3686/4885MAPK1 1292/4885HIF1A 3882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.