SCHEMBL25917464

SCHEMBL25917464

CCC(CCOc1cccc2c1cnn2C1CCCCO1)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ RXRA P19793 1/20 0.40
▸ RXRB P28702 1/20 0.40
▸ RXRG P48443 1/20 0.40
▸ MAPK8 P45983 5/20 0.38
▸ MAPK9 P45984 5/20 0.38
▸ CYP4F2 P78329 3/20 0.37
▸ CYP4A11 Q02928 3/20 0.37
▸ MAPK10 P53779 4/20 0.35
▸ PPARG P37231 3/20 0.34
▸ SCN9A Q15858 1/20 0.34
▸ BCHE P06276 2/20 0.33
▸ HTR6 P50406 2/20 0.33
▸ ATR Q13535 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25917465 0.91 RXRA (0.37) RXRARXRBRXRGMAPK8MAPK9
SCHEMBL25918088 0.89 RXRA (0.38) RXRARXRBRXRGMAPK8MAPK9
SCHEMBL25918087 0.84 MAPK8 (0.36) RXRARXRBRXRGMAPK8MAPK9
SCHEMBL30723809 0.83 RXRA (0.46) RXRARXRBRXRGMAPK8MAPK9
SCHEMBL25917489 0.83 RXRA (0.40) RXRARXRBRXRGCYP4F2CYP4A11
SCHEMBL30724136 0.81 ALOX5AP (0.39) RXRARXRBRXRGMAPK8MAPK9
SCHEMBL24179486 0.80 CYP4F2 (0.39) RXRARXRBRXRGMAPK8MAPK9
SCHEMBL25917394 0.80 RXRA (0.39) RXRARXRBRXRGMAPK8MAPK9
SCHEMBL7272765 0.78 RXRA (0.39) RXRARXRBRXRGMAPK8MAPK9
SCHEMBL25917467 0.78 RXRA (0.36) RXRARXRBRXRGMAPK8MAPK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242507-A1 INDAZOLE-FUSED CYCLIC COMPOUND Zhejiang Yangli Pharmaceutical Technology Co., Ltd. (CN) 2023-08-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242507-A1 INDAZOLE-FUSED CYCLIC COMPOUND SLC5A11, CYP11B2, CYP4F11 RXRA 3699/4885RXRB 3804/4885RXRG 3907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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