Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1459198 | 0.81 | TSHR (0.32) | ALDH1A1TSHRLMNAMAPT | |
| SCHEMBL2102966 | 0.79 | ALDH1A1 (0.38) | ALDH1A1NFKB1CYP1A2CYP2D6TSHR | |
| SCHEMBL3761218 | 0.79 | ALDH1A1 (0.43) | ALDH1A1NFKB1CYP1A2CYP2D6TSHR | |
| SCHEMBL31168893 | 0.79 | ALDH1A1 (0.43) | ALDH1A1NFKB1CYP1A2CYP2D6TSHR | |
| SCHEMBL9634396 | 0.75 | ALDH1A1 (0.36) | ALDH1A1NFKB1CYP1A2CYP2D6TSHR | |
| SCHEMBL1302209 | 0.72 | TSHR (0.45) | ALDH1A1CYP1A2TSHRHSD17B10NPC1 | |
| SCHEMBL1798315 | 0.72 | TSHR (0.45) | ALDH1A1CYP1A2TSHRHSD11B1NPC1 | |
| SCHEMBL30030347 | 0.71 | ALDH1A1 (0.34) | ALDH1A1MAPK1 | |
| SCHEMBL2586783 | 0.71 | ALDH1A1 (0.34) | ALDH1A1MAPK1 | |
| SCHEMBL11564077 | 0.71 | ALDH1A1 (0.37) | ALDH1A1MAPK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102869662-B | Organic electroluminescence device | 默克专利有限公司 | 2016-08-03 | — | — | CN | disclosed |
| US-9139582-B2 | Organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-09-22 | — | — | US | disclosed |
| US-9139582-B2 | Organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-09-22 | — | — | US | disclosed |
| US-9139582-B2 | Organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-09-22 | — | — | US | disclosed |
| US-20130053555-A1 | ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2013-02-28 | — | — | US | disclosed |
| US-20130053555-A1 | ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2013-02-28 | — | — | US | disclosed |
| CN-102869662-A | Organic electroluminescence devices | MERCK PATENT GMBH | 2013-01-09 | — | — | CN | disclosed |
| WO-2011137951-A1 | ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2011-11-10 | — | — | WO | disclosed |
| EP-0363584-B1 | Silylation method | GEN ELECTRIC (US) | 1994-09-14 | — | — | EP | disclosed |
| EP-0284873-B1 | SILYLATION METHOD | GENERAL ELECTRIC COMPANY (US) | 1993-09-01 | — | — | EP | disclosed |
| EP-0363584-A2 | Silylation method | GENERAL ELECTRIC COMPANY (US) | 1990-04-18 | — | — | EP | disclosed |
| US-4918197-A | CATALYTIC REACTION BETWEEN AROMATIC ACYLHALIDE AND HALOGENATED POLYSILANE | GENERAL ELECTRIC COMPANY (US) | 1990-04-17 | — | — | US | disclosed |
| EP-0284873-A2 | Silylation method | GENERAL ELECTRIC COMPANY (US) | 1988-10-05 | — | — | EP | disclosed |
| US-4709054-A | REACTION OF AROMATIC ACYL HALIDE AND HALOGENATED POLYSILANE, TRANSITION METAL CATALYST | GENERAL ELECTRIC COMPANY (US) | 1987-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053555-A1 | ORGANIC ELECTROLUMINESCENT DEVICES | L1CAM, PIEZO1, OR10J3 | ALDH1A1 183/4885NFKB1 3151/4885CYP1A2 1251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.