Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | SDCBP | O00560 | 1/20 | 0.41 |
| ▸ | SDC2 | P34741 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25918495 | 0.90 | MAP3K5 (0.47) | MAP3K5HDAC4HDAC1HDAC6CYP11B1 | |
| SCHEMBL25920003 | 0.83 | MET (0.47) | NPC1RAB9AADAM17SDCBPSDC2 | |
| SCHEMBL25920244 | 0.83 | NPC1 (0.43) | NPC1RAB9AMAP3K5SDCBPSDC2 | |
| SCHEMBL25920284 | 0.83 | NPC1 (0.43) | NPC1RAB9ASDCBPSDC2CYP1A2 | |
| SCHEMBL25920354 | 0.82 | NPC1 (0.50) | NPC1RAB9ASDCBPSDC2CYP1A2 | |
| SCHEMBL25919933 | 0.81 | CYP11B1 (0.46) | NPC1RAB9ACYP11B1CYP11B2CYP1A2 | |
| SCHEMBL25329776 | 0.80 | SDCBP (0.42) | MAP3K5HDAC4HDAC1HDAC6CYP11B1 | |
| SCHEMBL30477286 | 0.80 | SDCBP (0.42) | MAP3K5HDAC4HDAC1HDAC6CYP11B1 | |
| SCHEMBL25919865 | 0.80 | NPC1 (0.44) | NPC1RAB9AHDAC1HDAC6SDCBP | |
| SCHEMBL25918381 | 0.77 | NPC1 (0.53) | NPC1RAB9ASDCBPSDC2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023132606-A1 | NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS | 주식회사 이노보테라퓨틱스 | 2023-07-13 | — | — | WO | disclosed |