Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 10/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 10/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | WNT1 | P04628 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25919934 | 0.91 | CYP11B1 (0.49) | CYP11B1CYP11B2WNT1DYRK1AROCK2 | |
| SCHEMBL25920284 | 0.89 | NPC1 (0.43) | NPC1RAB9ACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL25918412 | 0.89 | NPC1 (0.50) | NPC1RAB9ACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL25920244 | 0.84 | NPC1 (0.43) | NPC1RAB9ACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL25920354 | 0.83 | NPC1 (0.50) | NPC1RAB9ACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL25920054 | 0.81 | NPC1 (0.45) | NPC1RAB9ACREBBPCYP2D6CYP2C9 | |
| SCHEMBL25918494 | 0.81 | NPC1 (0.45) | CYP11B1CYP11B2NPC1RAB9ADYRK1A | |
| SCHEMBL25331325 | 0.80 | MAPK1 (0.42) | CYP11B1CYP11B2WNT1DYRK1AROCK2 | |
| SCHEMBL30477299 | 0.80 | MAPK1 (0.42) | CYP11B1CYP11B2WNT1DYRK1AROCK2 | |
| SCHEMBL25920286 | 0.79 | NTSR1 (0.45) | CYP11B1CYP11B2MAPK1NTSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023132606-A1 | NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS | 주식회사 이노보테라퓨틱스 | 2023-07-13 | — | — | WO | disclosed |