Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 4/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 5/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | TACR3 | P29371 | 2/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25325413 | 0.88 | RIPK1 (0.36) | — | |
| SCHEMBL25326693 | 0.88 | RIPK1 (0.36) | — | |
| SCHEMBL25328898 | 0.87 | SMN1; SMN2 (0.34) | SLC6A9SMN1; SMN2TACR3GRM1CACNA1H | |
| SCHEMBL25324316 | 0.85 | RORC (0.35) | RORCNR1I2SLC6A9SLC9A1TACR3 | |
| SCHEMBL25327620 | 0.84 | SLC9A1 (0.35) | SLC6A9SMN1; SMN2SLC9A1NR3C2CACNA1H | |
| SCHEMBL25325663 | 0.81 | RIPK1 (0.39) | SMN1; SMN2SLC9A1 | |
| SCHEMBL25326815 | 0.81 | RORC (0.41) | RORC | |
| SCHEMBL25327901 | 0.81 | RORC (0.41) | RORC | |
| SCHEMBL25326809 | 0.81 | RORC (0.41) | RORC | |
| SCHEMBL25327905 | 0.81 | RORC (0.41) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146991-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |