Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 5/20 | 0.34 |
| ▸ | TACR3 | P29371 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25326961 | 0.88 | ACHE (0.33) | — | |
| SCHEMBL25918545 | 0.87 | RORC (0.33) | SMN1; SMN2SLC6A9TACR3GRM1CACNA1H | |
| SCHEMBL25326815 | 0.84 | RORC (0.41) | — | |
| SCHEMBL30522971 | 0.84 | RORC (0.41) | — | |
| SCHEMBL25326809 | 0.84 | RORC (0.41) | — | |
| SCHEMBL25327905 | 0.84 | RORC (0.41) | — | |
| SCHEMBL25327901 | 0.84 | RORC (0.41) | — | |
| SCHEMBL25326630 | 0.82 | HDAC4 (0.40) | SMN1; SMN2 | |
| SCHEMBL25324400 | 0.81 | PDK1 (0.45) | SLC6A9 | |
| SCHEMBL25328951 | 0.80 | RIPK1 (0.45) | SMN1; SMN2RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146991-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |